Is Cannabis Helpful or Harmful to Your Immune System?

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Is Cannabis Helpful or Harmful to Your Immune System?

Cannabis is being liked by people for the benefits it offers for managing various medical conditions. And with the growing awareness, people are applying for their MMJ card and some of them are going for their MMJ card Renewal. Consumers are getting experienced with the therapeutic potential of cannabis for managing autoimmune diseases, gastrointestinal disorders, and inflammation. 


But on the whole, how does it impact our immune system? If you are an experienced user, you might have wondered at times whether cannabis boosts or weakens your immune system. Does it make you more prone to infections or not? 

With our understanding of its effects widens, we also need to broaden our knowledge on how it impacts our immune system. Let’s take a look. 

The ECS, Immune System, And Cannabis

Our body’s immune system and the immune system share an elegant connection between them. The ECS generally acts like a gate-keeper for the immune system, where it prevents the onset of immense inflammatory responses, which results in a disease. ECS also impacts the functioning of immune cells. 

Both CB1 and CB2 receptors of the endocannabinoid system moderate the effects of cannabis on our immune system. Cannabinoids THC and CBD have distinctive effects on our immune system due to their extensive interaction with the cannabinoid receptors. 

A review of 2020 found that CBD suppresses some of the inflammatory responses of our immune system and even induces cell death in the immune system. Immune cell death helps in protecting a person by reducing inflammatory responses. 

Just like CBD, THC also restrains the immune activity, thus reducing the inflammatory responses. THC also changes the functioning of the immune cells that are responsible for antimicrobial activity.

How Cannabis Impacts Our Immune System?

When cannabis and the immune system are discussed together by the scientists, they often talk about the effects as immunosuppressive or immunomodulatory. Immunomodulation refers to a therapy that moderates the responses of the immune system. And when cannabis puts down the expression of the features of the immune system, this modulation form is known as immunosuppression. 

It’s important to point out the ability of cannabis to suppress or subdue the cells of the immune system that can be of use if our immune system is in need of suppression and is dysregulated. And if not, the immune suppression is of no help. 

In research of 2017, it was suggested that both THC and CBD have immunomodulatory effects on the intestinal lymphatic of our human system, which is the main host of our immune cells. More than half of the lymphocytes of our body are present in the lymphatic system. And these white blood cells or lymphocytes play a vital role in looking for and destroying the foreign body particles or cells that have penetrated our body. 

Another study found out that oral administration of THC and CBD along with fats results in extremely high levels of cannabinoids in the intestinal lymphatic system. The concentrations of THC in the lymph cells were higher than in plasma by 100 times, whereas the concentrations of CBD in the lymph cells were higher than in plasma by 250 times.

So, what does all this signify? For all those who have autoimmune diseases, and are either thinking of getting an MMJ card or are going to Renew MMJ card, cannabis can be of help for suppressing unhealthy inflammatory immune responses and in achieving higher concentrations of the lymphatic system more successfully.

Also Read: Is Medical Marijuana An Effective Treatment for Autoimmune Disorders?

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Location: Los Angeles, CA, USA

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